Table 2.
Univariate Regression Model | Multivariate Regression Model (Adjustment I)* | Multivariate Regression Model (Adjustment II)† | Multivariate Regression Model (Adjustment III)‡ | |||||
---|---|---|---|---|---|---|---|---|
OR (95% CI) | P Value | OR (95% CI) | P Value | OR (95% CI) | P Value | OR (95% CI) | P Value | |
In‐hospital death | 0.54 (0.50–0.58) | <0.001§ | 0.65 (0.60–0.71) | <0.001§ | 0.59 (0.55–0.64) | <0.001§ | 0.68 (0.63–0.74) | <0.001§ |
Recurrent myocardial infarction | 1.22 (0.97–1.54) | 0.088 | 1.23 (0.98–1.55) | 0.081 | 1.18 (0.93–1.49) | 0.165 | 1.18 (0.93–1.48) | 0.172 |
Pneumonia | 1.10 (1.04–1.17) | 0.002§ | 1.26 (1.19–1.35) | <0.001§ | 1.12 (1.05–1.20) | <0.001§ | 1.14 (1.07–1.21) | <0.001§ |
Deep venous thrombosis or thrombophlebitis | 1.41 (1.14–1.74) | 0.002§ | 1.25 (0.99–1.58) | 0.061 | 1.41 (1.14–1.74) | 0.001§ | 1.45 (1.18–1.80) | 0.001§ |
Pulmonary embolism | 1.10 (0.87–1.40) | 0.431 | 1.52 (1.23–1.87) | <0.001§ | 1.16 (0.92–1.46) | 0.221 | 1.23 (0.97–1.56) | 0.093 |
Acute kidney injury | 0.98 (0.90–1.07) | 0.645 | 1.12 (1.03–1.22) | 0.008§ | 0.88 (0.80–0.97) | 0.008§ | 1.02 (0.94–1.12) | 0.599 |
Shock | 0.78 (0.72–0.86) | <0.001§ | 0.79 (0.73–0.87) | <0.001§ | 0.73 (0.66–0.80) | <0.001§ | 0.80 (0.73–0.88) | <0.001§ |
Stroke (ischemic or hemorrhagic) | 1.00 (0.88–1.13) | 0.935 | 1.12 (0.99–1.27) | 0.077 | 0.94 (0.82–1.06) | 0.936 | 1.11 (0.98–1.26) | 0.098 |
Intracerebral bleeding | 1.44 (1.05–2.00) | 0.026§ | 1.46 (1.06–2.02) | 0.021§ | 1.27 (0.91–1.75) | 0.156 | 1.53 (1.10–2.11) | 0.010§ |
Gastrointestinal bleeding | 1.01 (0.85–1.20) | 0.909 | 1.16 (0.98–1.38) | 0.089 | 1.05 (0.88–1.24) | 0.605 | 1.11 (0.94–1.32) | 0.233 |
Transfusion of blood constituents | 1.24 (1.17–1.32) | <0.001§ | 1.35 (1.27–1.43) | <0.001§ | 1.20 (1.13–1.28) | <0.001§ | 1.24 (1.17–1.32) | <0.001§ |
Prolonged in‐hospital stay ≥10 d | 1.53 (1.47–1.59) | <0.001§ | 1.78 (1.70–1.85) | <0.001§ | 1.64 (1.57–1.71) | <0.001§ | 1.63 (1.56–1.71) | <0.001§ |
Prolonged in‐hospital stay ≥14 d | 1.54 (1.47–1.61) | <0.001§ | 1.79 (1.71–1.88) | <0.001§ | 1.63 (1.56–1.71) | <0.001§ | 1.64 (1.56–1.72) | <0.001§ |
OR indicates odds ratio.
Adjustment I: age and sex.
Adjustment II: age, sex, Charlson Index, and treatment year.
Adjustment III: age, sex, cancer, coronary artery disease, chronic obstructive pulmonary disease, essential arterial hypertension, renal insufficiency (glomerular filtration rate <60 mL/min per 1.73 m2), diabetes mellitus, atrial fibrillation/flutter, hyperlipidemia, and smoking.
P values of <0.05 were considered to be statistically significant.