Table 3.
Positive predictive values of myositis-blot antibodies in malignancies and autoimmune diseases other than IIM.
| MSA/MAA | AID (n = 39) | Malignancy (n = 22) | ||
|---|---|---|---|---|
| n * | PPV (%) | n * | PPV (%) | |
| Jo-1 | 4 | 20.00 | 4 | 20,00 |
| TIF1γ | 9 | 47.37 | 1 | 5,26 |
| MDA-5 | 3 | 20.00 | 2 | 13.33 |
| NXP-2 | 1 | 8.33 | 1 | 8.33 |
| SAE | 0 | 0.00 | 1 | 25.00 |
| PM-Scl100 | 14 | 53.85 | 5 | 19.23 |
| PM-Scl75 | 27 | 40.91 | 4 | 6.06 |
| PL-7 | 11 | 45.83 | 3 | 12.50 |
| EJ | 0 | 0.00 | 0 | 0.00 |
| OJ | 1 | 33.33 | 0 | 0.00 |
| PL-12 | 7 | 25.93 | 2 | 7.41 |
| SRP | 7 | 20.59 | 4 | 11.76 |
| Mi-2α | 3 | 27.27 | 1 | 9.09 |
| Mi-2β | 9 | 42.86 | 4 | 19.05 |
| Ku | 8 | 32.00 | 3 | 12.00 |
*
A single patient may be positive for more than one MSA/MAA.
AID, autoimmune disease other than IIM; MAA, myositis-associated antibody; MSA, myositis-specific antibody; PPV, positive predictive value.