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. 2020 Dec 10;9:40. doi: 10.1186/s13741-020-00171-3

Table 2.

A list of causes of hypochloremia

Mechanism Site of action Example
Loss of chlorides Gastrointestinal tract

Vomiting

Gastric drainage

Ileostomy with high waste products elimination rates

Kidney

Diuretics

Bartter’s syndrome

Gitelman’s syndrome

Excess intake of water (relative to chlorides) Congestive heart failure Hypotonic solution infusion
SIADH
Excess sodium intake (relative to chlorides) NaHCO3 infusion

SIADH the syndrome of inappropriate antidiuretic hormone secretion, NaHCO3 sodium bicarbonate. Adapted from Bandak G, Kashani KB. Chloride in intensive care units: a key electrolyte. F1000Res. 2017; 6:1930