Table 5.
Baseline characteristics of AP patients sorted by ratio of admission Cr/Alb
| Variables | Cr/Alb < 3.43 (n = 94) |
Cr/Alb ≥ 3.43 (n = 46) |
P value |
|---|---|---|---|
| Demographic characteristics | |||
| Age, years | 49.73 ± 13.00 | 50.17 ± 15.83 | 0.862 |
| Male, no. (%) | 62 (65.96) | 36 (78.26) | 0.136 |
| BMI, kg/m2 | 23.92 ± 3.46 | 24.83 ± 3.95 | 0.271 |
| Etiology, no. (%) | 0.317 | ||
| Post-ERCP | 4 (4.26) | 3 (6.52) | |
| Gallstone | 47 (50.00) | 19 (41.30) | |
| Hypertriglyceridemia | 15 (15.96) | 13 (28.26) | |
| Idiopathic | 28 (29.79) | 11 (23.91) | |
| History, no. (%) | |||
| Hypertension | 25 (26.60) | 14 (30.43) | 0.651 |
| Alcohol | 22 (23.40) | 12 (26.09) | 0.744 |
| Smoking | 21 (22.34) | 11 (23.91) | 0.770 |
| Diabetes mellitus | 8 (8.51) | 8 (17.39) | 0.242 |
| Fatty liver | 5 (5.32) | 1 (2.17) | 0.536 |
| CAD | 4 (4.26) | 1 (2.17) | 0.635 |
| Clinical presentation | |||
| Interval timea, days | 56.23 ± 51.14 | 35.18 ± 37.13 | 0.016* |
| Heart rate, bpm | 102.03 ± 20.38 | 116.45 ± 23.10 | < 0.001** |
| Temperature, ℃ | 37.13 ± 0.74 | 37.27 ± 1.02 | 0.412 |
| MAP, mmHg | 61.18 ± 37.54 | 67.66 ± 34.13 | 0.319 |
| Respiratory rate, bpm | 22.98 ± 5.60 | 25.95 ± 7.55 | 0.023* |
| Laboratory data in admission | |||
| Hemoglobin, g/L | 107.06 ± 26.30 | 107.3 ± 32.06 | 0.964 |
| BUN, mmol/L | 5.64 ± 3.13 | 17.83 ± 9.76 | < 0.001** |
| Creatinine, μmol/L | 59.29 ± 21.11 | 277.50 ± 187.02 | < 0.001** |
| CRP, mg/L | 102.52 ± 73.29 | 121.57 ± 83.89 | 0.262 |
| Albumin, g/L | 29.00 ± 5.71 | 26.80 ± 5.30 | 0.030* |
| WBC, × 109 cells/L | 11.94 ± 5.39 | 14.33 ± 7.28 | 0.039* |
| Platelet, × 109 cells/L | 239.08 ± 114.78 | 155.30 ± 93.27 | < 0.001** |
| TB, μmol/L | 39.55 ± 58.64 | 51.12 ± 67.60 | 0.307 |
| Score | |||
| APACHE II | 12.59 ± 6.76 | 21.21 ± 7.83 | < 0.001** |
| Post-operative complications, no. (%) | |||
| Sepsis | 21 (22.34) | 16 (34.78) | 0.117 |
| Electrolyte disorders | 14 (14.89) | 17 (36.96) | 0.003** |
| Respiratory failure | 13 (13.83) | 27 (58.70) | < 0.001** |
| Hemorrhage | 15 (15.96) | 19 (41.30) | 0.001** |
| Shock | 12 (12.77) | 24 (52.17) | < 0.001** |
| Renal failure | 7 (7.45) | 27 (58.70) | < 0.001** |
| Outcome, no. (%) | |||
| ICU duration, days | 58.75 ± 75.13 | 73.91 ± 64.24 | 0.251 |
| Re-operation | 25 (26.60) | 35 (76.09) | < 0.001** |
| Mortality | 3 (3.19) | 13 (28.26) | < 0.001** |
CAD coronary artery disease, MAP mean arterial pressure, CRP C-reactive protein, TB total bilirubin, BUN blood urea nitrogen, APACHE II Acute Physiology and Chronic Health Evaluation II
*Means P < 0.05, **means P < 0.001
aInterval time means the interval days between onset of AP and first debridement