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. 2020 Dec 9;19:250. doi: 10.1186/s12944-020-01425-1

Fig. 1.

Fig. 1

Fibrosis and oxidative stress markers in the liver and serum alpha-fetoprotein (AFP) of mice fed a control or low-methionine choline-deficient (LMCD) diet, and injected either with water (W) or diethylnitrosamine (DEN) (n = 4–8 mice per group). a Sirius red stained liver of the animals, b Collagen 1A1 (Col1A1) and alpha-smooth muscle actin (alpha-SMA) protein in the liver, c hepatic MDA levels, d MnSOD and 4-HNE in the liver, e AFP measured in serum. *** P <  0.001