Table 2.
Comparison of comorbidities in patients with adverse drug reactions between younger patients and older adults
| Total N = 14,864 (%) |
< 65 years N = 11,427 (%) |
≥ 65 years N = 3437 (%) |
P value | |
|---|---|---|---|---|
| Comorbid conditions | ||||
| Injury, poisoning, and other consequences of external causes | 3771 (20.0) | 3246 (28.4) | 525 (15.3) | < 0.001 |
| Diseases of the digestive system | 3496 (18.6) | 2676 (23.4) | 820 (23.9) | 0.594 |
| Neoplasms | 3375 (17.9) | 2462 (21.5) | 913 (26.6) | < 0.001 |
| Diseases of the respiratory system | 2744 (14.6) | 2207 (19.3) | 537 (15.6) | < 0.001 |
| Diseases of the skin and subcutaneous tissue | 2112 (11.2) | 1807 (15.8) | 305 (8.9) | < 0.001 |
| Diseases of the circulatory system | 2057 (10.9) | 1222 (10.7) | 835 (24.3) | < 0.001 |
| Diseases of the musculoskeletal system and connective tissue | 1821 (9.7) | 1313 (11.5) | 508 (14.8) | < 0.001 |
| Diseases of the genitourinary system | 1666 (8.8) | 1244 (10.9) | 422 (12.3) | 0.028 |
| Certain infectious and parasite disease | 1644 (8.7) | 1304 (11.4) | 340 (9.9) | 0.010 |
| Endocrine, nutritional, and metabolic diseases | 1558 (8.3) | 1087 (9.5) | 471 (13.7) | < 0.001 |
| Diseases of the nervous system | 1228 (6.5) | 959 (8.4) | 269 (7.8) | 0.283 |
Values represent numbers of patients with percentages in parentheses. Plus-minus values are means ± standard deviations. P values were obtained from the chi-square test with Yates’ correction