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. 2018 Nov 1;11(8):649–664. doi: 10.1093/jmcb/mjy059

Figure 7.

Figure 7

Survival analysis results of DNB genes and mutational genes on two independent datasets. (A and B) The higher level of the combined expression index of DNBs is associated with the poorer survival in the TCGA dataset (A) and the EBI dataset (B). (C and D) Mutant ARFGAP1 (C) or FBF1 (D) is associated with the poor survival in the TCGA dataset. (E) In the EBI dataset, homozygous gene mutation in FBF1 is associated with the poor survival comparing with heterozygous gene mutation in FBF1. (F) Mutant ZBTB17 is associated with the poor survival. (G) The patients with ARFGAP1, FBF1, or ZBTB17 mutation are associated with the poor survival. The survival analysis results on individual DNB genes are given in Supplementary Figure S5. Survival analyses validate that DNB genes and mutant genes are associated with poor survival of breast cancer patients.