Table 3.
Summary of killer-cell immunoglobulin-like receptor (KIR)*IMP and KIR probe interpretation (KPI) gene predictions.
| gene | reference freq. | KIR*IMP freq. | KPI freq. | KIR*IMP - KPI | KIR*IMP & KPI agreement | KIR*IMP - reference | KPI - reference |
|---|---|---|---|---|---|---|---|
| 2DS2 | 53-54% | 39% | 52% | −13% | 72% | −14% | −1% |
| 2DL2 | 53-54% | 39% | 51% | −12% | 72% | −14% | −2% |
| 2DL3 | 90% | 96% | 92% | 4% | 92% | 6% | 2% |
| 2DP1 | 96% | 99% | 97% | 2% | 97% | 3% | 1% |
| 2DL1 | 96% | 99% | 97% | 2% | 97% | 3% | 1% |
| 3DP1 | 100% | 100% | 100% | 0% | 100% | 0% | 0% |
| 2DL4 | 100% | 100% | 100% | 0% | 100% | 0% | 0% |
| 3DL1 | 93%–94% | 96% | 96% | 0% | 100% | 2% | 2% |
| 3DS1 | 38%–44% | 33% | 35% | −2% | 97% | −5% | −3% |
| 2DL5 | 53%–56% | 38% | 47% | −9% | 87% | −15% | −6% |
| 2DS3 | 30%–31% | 10% | 29% | −18% | 81% | −20% | −1% |
| 2DS5 | 30%–36% | 25% | 27% | −2% | 96% | −5% | −3% |
| 2DS4 | 92%–94% | 96% | 96% | 0% | 100% | 2% | 2% |
| 2DS1 | 43%–44% | 33% | 34% | −1% | 98% | −10% | −9% |
| average | 92% | ||||||
Frequencies relative to Genome of the Netherlands (GoNL) cohort of 748 individuals. The abbreviated gene name is in column 1. Column 2 lists the reference frequencies from The Allele Frequency Net Database. The predicted frequencies from KIR*IMP and KPI are in columns 3 and 4, respectively. The delta between KIR*IMP and KPI is shown in the column 5. Column 6 shows the agreement between KIR*IMP and KPI. Column 7 shows the delta between KIR*IMP and the reference. Column 8 shows the delta between KPI and the reference. Frequencies with differences >10% are in bold.