Table 4.
Inhibition of biofilm and destruction of preformed biofilm in Staphylococcus aureus by compounds 1–3, 5, 6.
| Compounds | Inhibition of Biofilm Formation (%) | Destruction of Preformed Biofilm (%) |
|---|---|---|
| 1 | - | - |
| 2 | 65 (250 µg/mL) 43 (125 µg/mL) |
36 (250 µg/mL) 31 (125 µg/mL) |
| 3 | 75 (250 µg/mL) 59 (125 µg/mL) |
57 (250 µg/mL) 48 (125 µg/mL) |
| 4 | n.t | n.t |
| 5 | 79 (250 µg/mL) 77 (62.5 µg/mL) 61 (15.6 µg/mL) |
75 (250 µg/mL) 65 (62.5 µg/mL) 31 (15.6 µg/mL) |
| 6 | 76 (250 µg/mL) 70 (62.5 µg/mL) 19 (15.6 µg/mL) |
73 (250 µg/mL) 59 (62.5 µg/mL) 40 (15.6 µg/mL) |
| Microporenic acid A | 83 (250 µg/mL) 81 (62.5 µg/mL) 48 (15.6 µg/mL) |
71 (250 µg/mL) 70 (62.5 µg/mL) 39 (15.6 µg/mL) |
n.t: not tested, (-) no activity.