ACM |
Arrhythmogenic cardiomyopathy |
AFM |
Atomic force microscopy |
AJ |
Adhesive junction |
AP |
Action potential |
APD |
Action potential duration |
ARVC |
Arrhythmogenic right-ventricular cardiomyopathy |
BTHS |
Barth syndrome |
CaT |
Calcium transient |
CFCS |
Cardio-facio-cutaneous syndrome |
CHF |
Chronic heart failure |
CiPA |
Comprehensive in vitro proarrhythmia assay |
CM |
Cardiomyocyte |
CPVT |
Catecholaminergic polymorphic ventricular tachycardia |
CVD |
Cardiovascular disease |
DAD |
Delayed afterdepolarization |
DCM |
Dilated cardiomyopathy |
DMD |
Duchenne muscular dystrophy |
EAD |
Early afterdepolarization |
EC |
Endothelial cell |
ECC |
Excitation–contraction coupling |
ECG |
Electrocardiogram |
ECM |
Extracellular matrix |
EHT/EHM |
Engineered heart tissue/engineered heart muscle |
ER |
Endoplasmic reticulum |
ERR |
Estrogen-related receptors (including α, β, and γ) |
FAO |
Fatty-acid oxidation |
FFR |
Force–frequency relationship |
FGF |
Fibroblast growth factor |
FP |
Field potential |
GAA |
Acid-α-glucosidase |
GATA |
GATA family transcription factor |
GC |
Glucocorticoid |
GJ |
Gap junction |
HCM |
Hypertrophic cardiomyopathy |
HCN4 |
Hyperpolarization-activated cyclic nucleotide-gated potassium channel 4 |
hERG |
Human ether-à-go-go-related gene |
HF |
Heart failure |
HFrEF |
Heart failure with reduced ejection fraction |
HIF1 |
Hypoxia-inducible factor 1-alpha |
hESC |
Human embryonic stem cell |
hiPSC |
Human induced pluripotent stem cell |
hiPSC-CM |
Human induced pluripotent stem cell-derived cardiomyocyte |
HOPX |
Homeodomain-only protein homeobox |
ID |
Intercalated disc |
IGF |
Insulin-like growth factor |
JiCSA |
Japan iPS cardiac safety assessment |
LDHA |
Lactate dehydrogenase A |
LQT1/2/3 |
Long QT syndrome type 1/type 2/type 3 |
LQTS |
Long QT syndrome |
LTCC |
L-type calcium channel |
MEA |
Multielectrode array |
MEF2 |
Myocyte enhancer factor-2 |
miRNA/miR |
MicroRNA |
MMP |
Mitochondrial membrane potential |
MS |
Mass spectrometry |
MSC |
Mesenchymal stem cell |
MTF |
Muscle thin film |
NCX |
Na+–Ca2+ exchanger |
NMR |
Nuclear magnetic resonance spectroscopy |
Non-CM |
Noncardiomyocyte |
NRG1 |
Neuregulin-1 |
NRs |
Nuclear receptor superfamily |
NT-proBNP |
N-terminal pro B-type natriuretic peptide |
OXPHOS |
Oxidative phosphorylation |
PD |
Pompe disease |
pF |
Picofarad |
PGC-1 |
Peroxisome proliferator-activated receptor-γ co-activator 1-alpha/beta |
PPAR |
Peroxisome proliferator-activated receptor |
RA |
Retinoic acid |
RXR |
Retinoid X receptor |
RyR |
Ryanodine receptor |
SERCA |
Sarco/endoplasmic reticulum Ca2+ ATPase |
SR |
Sarcoplasmic reticulum |
SRF |
Serum response factor |
ssTnI |
Slow skeletal muscle troponin I |
T3 |
Triiodothyronine |
TdP |
Torsade de pointes |
TGF-β |
Transforming growth factor beta |
TNNT |
Troponin |
TTN |
Titin |
T-tubule |
Transverse tubule |
VEGF |
Vascular endothelial growth factor |
α-MHC |
Myosin heavy chain α-isoform |
β-MHC |
Myosin heavy chain β-isoform |