Table 1.
Classification | Family/Type | Enzymes | References | ||
---|---|---|---|---|---|
HMTs | PRMTs | TYPE I | PRMT 1, PRMT 3, PRMT 4/CRM1, PRMT-6, PRMT-8 | [42,43,44,55,56] | |
TYPE II | PRMT 5, PRMT 9/FBXO11 | [57] | |||
TYPE III | PRMT7 | [57] | |||
KMTs | SET | SET I | EZH I, H3K27 | [46,47] | |
SET 2 | NSD1-3, SETD2, SMYD2 | [58,59,60,61] | |||
SUV39 | SUV39H1, SUV39H2, G9a GLP, ESET//SETDB1 CLLL8/SETDB2 |
[62,63,64,65,66] | |||
RIZ | RIZ 1, BLIMP1/PRDM1 PFM1/CRS2 |
[67] | |||
Nongroup | SET7/9, SET8, SUV4-20H1 SUV4-20H2 |
[61,68] | |||
Seven-β-strand (7BS) | Dot1/DOT1L | [49] | |||
HDMs | KDM1 | KDM1A, KDM1B | [36] | ||
JMJC | KDM2-7/8 | [51,52] | |||
HATs | GNAT | KAT2A, KAT2B | [69,70] | ||
MYST | KAT7, KAT8, KAT5, KAT6A KAT6B |
[71,72] | |||
p300/CBP | KAT3B | [73] | |||
Transcription coactivators | KAT4, KAT12 | [74] | |||
Steroid receptor | KAT13A, KAT13B KAT13C, KAT13D |
[74] | |||
Cytoplasmic | HAT1, HAT4 | [75] | |||
HDACs | CLASS 1 | HDAC1, HDAC2 HDAC3, HDAC8 |
[76,77,78,79] | ||
CLASS II a | HDAC4, HDAC5 HDAC7, HDAC9 |
[80,81,82,83] | |||
CLASS II b | HDAC6, HDAC10 | [84] | |||
CLASS III | Sirtuins (SIRT 1-7) | [85] | |||
CLASS IV | HDAC 11 | [86] |