Skip to main content
. 2020 Nov 24;21(23):8894. doi: 10.3390/ijms21238894

Table 1.

Various classes/families/subtypes of enzymes involved in histone methylation and acetylation reactions.

Classification Family/Type Enzymes References
HMTs PRMTs TYPE I PRMT 1, PRMT 3, PRMT 4/CRM1, PRMT-6, PRMT-8 [42,43,44,55,56]
TYPE II PRMT 5, PRMT 9/FBXO11 [57]
TYPE III PRMT7 [57]
KMTs SET SET I EZH I, H3K27 [46,47]
SET 2 NSD1-3, SETD2, SMYD2 [58,59,60,61]
SUV39 SUV39H1, SUV39H2, G9a
GLP, ESET//SETDB1
CLLL8/SETDB2
[62,63,64,65,66]
RIZ RIZ 1, BLIMP1/PRDM1
PFM1/CRS2
[67]
Nongroup SET7/9, SET8, SUV4-20H1
SUV4-20H2
[61,68]
Seven-β-strand (7BS) Dot1/DOT1L [49]
HDMs KDM1 KDM1A, KDM1B [36]
JMJC KDM2-7/8 [51,52]
HATs GNAT KAT2A, KAT2B [69,70]
MYST KAT7, KAT8, KAT5, KAT6A
KAT6B
[71,72]
p300/CBP KAT3B [73]
Transcription coactivators KAT4, KAT12 [74]
Steroid receptor KAT13A, KAT13B
KAT13C, KAT13D
[74]
Cytoplasmic HAT1, HAT4 [75]
HDACs CLASS 1 HDAC1, HDAC2
HDAC3, HDAC8
[76,77,78,79]
CLASS II a HDAC4, HDAC5
HDAC7, HDAC9
[80,81,82,83]
CLASS II b HDAC6, HDAC10 [84]
CLASS III Sirtuins (SIRT 1-7) [85]
CLASS IV HDAC 11 [86]