Aβ	Amyloid Beta
AD	Alzheimer ’s disease
ALS	Amyotrophic Lateral Sclerosis
ALT	Alanine transaminase
APP	Amyloid Precursor Protein
AMBRoSIA	A Multicenter Biomarker Resource Strategy in ALS
AST	Aspartate transaminase
ATP	Adenosine Triphosphate
CNS	Central Nervous System
CRISPR	Clustered regularly interspaced short palindromic repeat
DNA	Deoxyribonucleic Acid
2,3-DPG	2,3-diphosphoglycerate
ECAR	extracellular acidification rate
ETC	Electron Transport Chain
FDG-PET	fluorodeoxyglucose-positron emission tomography
GA3PDH	glyceraldehyde-3-phosphate dehydrogenase
GFAP	Glial fibrillary acidic protein
HIF1	Hypoxia-inducible factor 1
HK	Hexokinase
6OHDA	6-hydroxydopamine
LCL	Lymphoblastic Cell Lines
LDH	Lactate Dehydrogenase
MEF	Mouse embryonic fibroblasts
MPP+	Methyl-4-phenylpyridinium
NAD	Nicotinamide adenine dinucleotide
NADPH	Nicotinamide adenine dinucleotide phosphate
ND	Neurodegenerative disease
OxPHOS	Oxidative phosphorylation
PBMCs	Peripheral blood mononuclear cells
PD	Parkinson’s disease
PDK	Pyruvate dehydrogenase kinase
PDK4	Pyruvate dehydrogenase lipoamide kinase isozyme 4
PFK	Phosphofructokinase
PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGK	Phosphoglycerate kinase
PK	Pyruvate Kinase
PINK1	PTEN-induced kinase 1
PPS	Pentose Phosphate Shunt
RBC	Red Blood Cells
ROS	Reactive Oxygen Species
SN	Substantia Nigra Pars Compacta
TCA	Tricarboxylic Acid Cycle
TIGAR	TP53 Induced Glycolysis Regulatory Phosphatase