Table 1.

Craniofacial bone analyses in Crtap^−/− vs Crtap^+/+ mice

	Frontal		Parietal		Nasal
	Crtap+/+	Crtap−/−	Crtap+/+	Crtap−/−	Crtap+/+	Crtap−/−
BV (mm3)	0.033 ± −0.005	0.023 ± 0.002* (−30%)	0.034 ± 0.002	0.024 ± 0.002* (−29%)	0.039 ± 0.012	0.025 ± 0.011* (−36%)
BV/TV	0.79 ± 0.10	0.86 ± 0.09	0.95 ± 0.02	0.91 ± 0.05	0.49 ± 0.01	0.34 ± 0.02* (−31%)
BMC (mg)	0.022 ± 0.003	0.017 ± 0.002* (−23%)	0.026 ± 0.002	0.018 ± 0.002* (−31%)	0.41 ± 0.1	0.30 ± 0.01* (−27%)
BMD (mg/cc)	680 ± 51	712 ± 60	769 ± 22	741 ± 30	518 ± 76	419 ± 98* (−19%)
TMC (mg)	0.020 ± 0.002	0.015 ± 0.003* (−25%)	0.025 ± 0.002	0.017 ± 0.002* (−32%)	029 ± 0.010	0.18 ± 0.008* (−38%)
TMD (mg/cc)	759 ± 30	753 ± 42	784 ± 18	771 ± 13	734 ± 40	707 ± 39

Note. MicroCT was used to measure total bone volume (BV). bone volume fraction (BV/TV). bone mi neral content (BMC), bone mineral density (BMD), tissue mineral content (TMC), and tissue mineral density (TMD) in cranial and nasal bones of Crtap^+/+ and Crtap^−/− mice.

^“*”indicate statistical significance between genotypes, P < .05. Percentage changes between genotypes are also shown.