Figure A2.
Inhibitory effects of components of vitamin B in rice bran on HIF activity. Quantitative analysis of HIF-reporter luciferase assay using ARPE-19 cells (n = 3 per group) showed that vitamin B6 dramatically inhibited CoCl2-induced HIF activity more than any other components in rice bran. *** p < 0.001, ### p < 0.001, compared with no treatment and 200 µM of CoCl2 treatment, respectively. A bar graph was presented as mean ± standard deviation. The data were analyzed using one-way ANOVA followed by a Bonferroni post hoc test. Solvents, rice bran: DMSO; vitamin B: water.