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. Author manuscript; available in PMC: 2020 Dec 10.
Published in final edited form as: Immunohorizons. 2020 Aug 20;4(8):508–519. doi: 10.4049/immunohorizons.2000026

Fig 3. Protein levels of MHC-related molecules decrease in lung macrophages exposed to Pseudomonas aeruginosa EVs for up to 48 hours.

Fig 3.

MHC class II-related proteins CD74 and CD9 decrease after 48 hours, however show some variability at the 24 hour time point. HLA-DR subunits were modestly diminished at 48 hours post P.a. EV-treatment. TLR engagement has been reported to partly stabilize HLA-DR surface molecules, potentially leading to a modest depletion at the protein level. A complement of four additional subjects were used for cellular protein studies (see methods section). Responses were similar in 3 of 4 subjects.