Fig 4. Multiple DA release events from synaptic terminal.

A: Simulated concentration [μM] with 3000 molecules released per event. B: Associated equilibrium receptor binding (Michaelis-Menten kinetics). C: Associated slow receptor binding. Percentage of binding increases with each release event inside and close to release site. At 2μm distance from the synapse center increments become insignificantly small. D: Associated fast receptor binding. Again, at 2μm distance from the synapse center receptor binding becomes insignificantly low.