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. 2020 Dec 2;9:e61487. doi: 10.7554/eLife.61487

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© 2020, Blanden et al

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

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Figure 5. — 12 common p53 mutants were generated by site-directed mutagenesis and expressed in p53-null H1299 cells. Cells were treated with ZMC1 and the cell growth inhibition was measured by Calcein AM assay. EC₅₀ values were calculated using nonlinear-fit curves by GraphPad Prism software.