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Summary of pharmacokinetic parameters for AB1904Am15 and L0H0 in hFcRn transgenic mouse (mean ± SD).
| Treatment | AB1904Am15 (n = 4) | L0H0 (n = 4) |
|---|---|---|
| t1/2 (day) | 35.1 ± 26.7 | 12.9 ± 1.8 |
| Tmax (day) | 5.3 ± 3.9 | 2.8 ± 2.9 |
| Cmax (μg/ml) | 58.4 ± 6.6 | 53.7 ± 6.4 |
| AUClast (day ∗ μg/ml) | 1282.8 ± 228.4 | 898.7 ± 155.7 |
| AUCINF_obs (day ∗ μg/ml) | 1959.1 ± 719.1 | 989.2 ± 194.7 |
