Table 3.
Sensitivity analyses of studies on AKI predictors
| Parameter | n | Pooled adjusted OR (95% CI) |
|---|---|---|
| Design | ||
| Retrospective | 7 | 2.14 (1.47-3.13) |
| Prospective | 4 | 2.79 (1.99-3.93) |
| Size (patients) | ||
| ≤200 | 7 | 2.11 (1.43-3.13) |
| >200 | 4 | 2.86 (2.11-3.89) |
| Year reported | ||
| ≤2000 | 3 | 2.58 (1.67-3.97) |
| >2000 | 8 | 2.23 (1.58-3.16) |
| AKI definition | ||
| Fixed SCr increase | 4 | 1.96 (1.11-3.49) |
| Graded SCr increasea | 3 | 2.04 (1.13-3.71) |
| Otherb | 4 | 2.90 (2.24-3.76) |
AKI Acute kidney injury; BUN blood urea nitrogen; CI confidence interval; GFR glomerular filtration rate; n number of studies; OR odds ratio; RIFLE risk of renal dysfunction, injury to the kidney, failure of kidney function, loss of kidney function and end-stage kidney disease; SCr serum creatinine
aDetermined by baseline SCr
bSCr or BUN increase, RIFLE GFR criteria, AKIN creatinine criteria, or dialysis