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. 2020 Nov 27;11:590884. doi: 10.3389/fneur.2020.590884

Figure 2.

Figure 2

Effect of Rapamycin on pathological changes of tissue in EAE mice. (A) HE staining of the tissue in the periventricular and spinal cord at 21 day post immunization (left: Normal group, mid: EAE group, right: Rapamycin group, 200x,400x magnification). (B) Weil staining of tissue in the periventricular and spinal cord at 21 day post immunization (left: Normal group, mid: EAE group, right: Rapamycin group, 200x, 400x magnification). (C) Anti-Myelin Basic Protein antibody (MBP antibody) has been detected in spinal cord to demonstrate the retention of more myelin (left: Normal group, mid: EAE group, right: Rapamycin group, 200x,400x magnification). *P < 0.05, **P < 0.01, ***P < 0.001.