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. 2020 Nov 3;35(Suppl 3):903–909. doi: 10.1007/s11606-020-06252-9

Table 2.

Transition Probabilities for Patients Receiving High-dose, Long-term Opioid Therapy (HLOT) at the Start of Each Fiscal Year Between 2014 and 2018

FY HLOT Non-HLOT Discontinued Death Total
2014 35,921 (72%) 8935 (18%) 3128 (6.3%) 1724 (3.5%) 49,708
2015 31,479 (72%) 7967 (18%) 2992 (6.8%) 1484 (3.4%) 43,922
2016 26,604 (69%) 7693 (20%) 2786 (7.3%) 1225 (3.2%) 38,308
2017 20,051 (64%) 7638 (25%) 2460 (7.9%) 1026 (3.3%) 31,175
2018 14,732 (64%) 5747 (25%) 1798 (7.8%) 722 (3.1%) 22,999

Markov chain models were calculated for fiscal years (FY) 2014 through 2018. The proportion of patients who received high-dose, long-term opioid therapy (HLOT) at the beginning of the FY and stayed in HLOT, transitioned to non-HLOT, discontinued, or died were calculated for each FY and presented in the table above