Table 1.

Past-Year Substance Use Prevalence Among Middle-aged and Older Adults by Sexual Orientation in the United States, 2015–2017

	Heterosexual adults ages ≥ 50 (n = 25,217), weighted % (95% CI)	LGB adults ages ≥ 50 (n = 663), weighted % (95% CI)	X2 p value	aOR (95% CI)*
Cannabis use (any)	6.46 (6.07, 6.87)	17.70 (13.60, 22.80)	< 0.001	2.21 (1.58, 3.08)
Non-medical cannabis use	5.45 (5.13, 5.79)	13.90 (10.20, 18.70)	< 0.001	1.96 (1.36, 2.83)
Alcohol use	62.60 (61.7, 63.5)	70.60 (66.30, 74.60)	0.001	1.33 (1.06, 1.66)
Alcohol use disorder†	3.36 (3.10, 3.64)	5.29 (3.62, 7.67)	0.02	1.20 (0.78, 1.84)
Nicotine dependence‡	6.48 (6.18, 6.80)	8.16 (5.98, 11.0)	0.15	0.97 (0.68, 1.38)
Cocaine use	0.65 (0.54, 0.79)	2.33 (1.21, 4.42)	< 0.001	1.86 (0.88, 3.89)
Methamphetamine use	0.30 (0.24, 0.37)	0.79 (0.31, 2.04)	0.05	1.75 (0.63, 4.87)
Prescription opioid misuse	2.34 (2.15, 2.55)	4.72 (3.19, 6.94)	0.001	1.66 (1.09, 2.53)
Prescription sedative misuse	0.49 (0.39, 0.61)	0.93 (0.50, 1.69)	0.05	1.31 (0.65, 2.65)
Prescription tranquilizer misuse	1.07 (0.92, 1.25)	3.62 (2.11, 6.17)	< 0.001	2.39 (1.31, 4.34)
Prescription stimulant misuse	0.27 (0.22, 0.34)	0.76 (0.30, 1.91)	0.02	1.85 (0.68, 5.02)

*Adjusted for age, gender, race, family income, and marital status. ^†Based on the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition.^{4 ‡}Based on Nicotine Dependence Syndrome Scale.⁵ LGB, lesbian, gay, or bisexual; aOR adjusted odds ratio