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. 2020 Nov 27;12:591666. doi: 10.3389/fnagi.2020.591666

Table 3.

The mean meta-analysis: gray matter volume reductions in MSA-C patients relative to HCs.

Regions No. of voxels Maximum MNI coordinates (x, y, z) SDM-Z value p-value Egger test (p-value) Clusters' breakdown Jackknife sensitivity analysis
Area 1 5,384 −4, −52, −14 −5.307 ~0 0.917 Left cerebellar hemispheric lobule III
Left cerebellar hemispheric lobule IV/V
Left cerebellar hemispheric lobule VI
Right cerebellar hemispheric lobule III
Right cerebellar hemispheric lobule IV/V
Right cerebellar hemispheric lobule VI
Left cerebellar crus I
Cerebellar vermic lobule III
Cerebellar vermic lobule IV/V
Cerebellar vermic lobule VI
Cerebellar vermic lobule VIII
Cerebellar vermic lobule X
Left fusiform gyrus
Left lingual gyrus
Right lingual gyrus
5 out of 5
5 out of 5
5 out of 5
5 out of 5
5 out of 5
5 out of 5
5 out of 5
5 out of 5
5 out of 5
5 out of 5
5 out of 5
5 out of 5
5 out of 5
5 out of 5
5 out of 5
Area 2 269 52, 2, −14 −2.667 <0.001 0.673 Right temporal pole, superior temporal gyrus
Right temporal pole, middle temporal gyrus
Right superior temporal gyrus
3 out of 5
3 out of 5
3 out of 5

MSA-C, multiple system atrophy with predominant cerebellar ataxia; HCs, healthy controls; MNI, Montreal Neurological Institute; SDM, Seed-based d Mapping.