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. 2020 Nov 27;10:598192. doi: 10.3389/fonc.2020.598192

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Copyright © 2020 Zhao, Xue, Hao, Jiang and Zheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The clinicopathological and prognostic significances of BTG1 mRNA in colorectal cancer. TCGA database showed that BTG1 was lower expressed in well-, moderately, and poorly differentiated (non-MUC) than in mucinous (MUC) adenocarcinomas (A, P < 0.05). BTG1 expression was positively correlated with K-ras and BRAF mutation of colorectal cancers (A, P < 0.05). BTG1 expression was negatively related to overall survival rate of the patients with colorectal cancer (B, P < 0.05). The prognostic significance of BTG1 mRNA expression was also analyzed using Kaplan–Meier plotter database (C). HR, hazard ratio.