Table 6.

Relationship between BTG1 expression and clinicopathological features of colorectal cancer.

Clinicopathologicalfeatures	n	BTG1 expression
		−	+	++	+++	PR (%)	P value
Age(years)							0.812
<65	280	95	53	76	56	66.1
≥65	205	72	40	51	42	64.9
Sex							0.981
Male	261	88	51	72	50	66.3
Female	224	79	42	55	48	64.7
Depth of invasion							<0.001
Tis–T2	126	57	27	28	14	54.8
T3–T4	338	104	62	93	79	69.2
Lymphatic invasion							0.146
−	197	75	40	52	30	61.9
+	207	71	36	55	45	65.7
Venous invasion							0.003
−	195	78	42	47	28	60.0
+	196	59	33	57	47	69.9
Lymph node metastasis							0.019
−	259	97	53	65	44	62.5
+	207	62	37	57	51	70.0
Liver metastasis							0.090
−	450	158	88	117	87	64.9
+	28	7	4	8	9	75.0
Distant metastasis							0.041
−	445	158	85	116	86	64.5
+	36	7	8	10	11	80.6
TNM staging							0.002
0–II	247	95	53	60	39	61.5
III–IV	215	62	37	60	56	71.2
Differentiation							0.193
Well-differentiated	197	72	43	47	35	63.5
Moderately differentiated	231	72	37	71	51	68.8
Poorly differentiated	32	14	4	7	7	56.3

PR, positive rate; T_is, carcinoma in situ; T₁, lamina propria and submucosa; T₂, muscularis propria; T₃, subserosa and exposure to serosa_; T₄, invade other organs or perforate visceral peritoneum; TNM, tumor-node-metastasis.