FIGURE 2.

Effects of SNX27 overexpression on anxiety-like behavior and social interaction. (A) Time spent in the center, number of entries into the center, and distance traveled in open field test were quantified and analyzed. (B) In the elevated plus maze test, WT and Tg mice were assessed for percentage of time spent in the open arms, percentage of entries into the open arms, and total distance they traveled. (C) The durations of social interaction were measured in a 10-min social interaction test. Representative traces are shown. Data represent mean ± s.e.m. (WT, n = 14; Tg, n = 16). *P < 0.05, **P < 0.01 (two-tailed unpaired t test).