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. 2020 Nov 27;8:595357. doi: 10.3389/fcell.2020.595357

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Copyright © 2020 Huo, Gao, Zheng, Zhao, Guo, Zhang, Zeng, Cheng, Gu, Zhang, Zhu, Luo, Zhang, Zhou, Zhang, Sun, Xu and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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hSNX27 transgenic mice displayed enhanced excitatory synaptic function. (A) (A, top) Representative traces of mEPSCs. mEPSCs were recorded at a holding potential of –70 mV. Scale bar = 1 s, 5 pA. (A, bottom) Quantitative analysis of the amplitude (left) and frequency (right) of mEPSCs. n = 15 cells per group. Data represent mean ± s.e.m. (B) (B, top) Representative traces of mIPSCs. mIPSCs were recorded at a holding potential of 0 mV. Scale bar = 1 s, 10 pA. (B, bottom) Quantitative analysis of the amplitude (left) and frequency (right) of mIPSCs. n = 20 cells per group. Data represent mean ± s.e.m. ns, not significant, *P < 0.05 (two-tailed unpaired t test).