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Schematic of N6-methylation/demethylation and m6A-regulated RNA processing. RNAs are N6-methylated by the writers and reversely N6-demethlyated by the erasers. The processes of methylation/demethylation may be guided by specific transcriptional factors, RBPs and histone modifications. N6-methylated RNAs are further recognized and processed by a serious of readers and associated factors.
