Table 2.
In-hospital outcomes among all patients according to PPIs use before and after PSM.
| Clinical endpoint | Before PSM | After PSM | |||||
|
PPIs
(n = 15, 792) |
No PPIs
(n = 7588) |
P |
PPIs
(n = 7169) |
No PPIs
(n = 7169) |
P | ||
| Data are presented as n (%). PSM: propensity score matching; PPIs: proton pump inhibitors; MACCE: major adverse cardiovascular and cerebrovascular events; GIB: gastrointestinal bleeding. | |||||||
| Primary endpoint | |||||||
| MACCE | 647 (4.1%) | 372 (4.9%) | 0.0056 | 286 (4.0%) | 337 (4.7%) | 0.0025 | |
| Secondary endpoint | |||||||
| Cardiac death | 569 (3.6%) | 349 (4.6%) | 0.0004 | 251 (3.5%) | 315 (4.4%) | 0.0008 | |
| Re-infarction | 111 (0.7%) | 30 (0.4%) | 0.0094 | 43 (0.6%) | 28 (0.4%) | 0.0098 | |
| Stroke | 142 (0.9%) | 38 (0.5%) | 0.0055 | 65 (0.9%) | 28 (0.4%) | 0.0031 | |
| GIB | 252 (1.6%) | 23 (0.3%) | < 0.0001 | 108 (1.5%) | 20 (0.3%) | < 0.0001 | |