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. 2020 Nov 27;8:592518. doi: 10.3389/fcell.2020.592518

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Copyright © 2020 Maia, Otake, Poças, Carvalho, Beck, Magalhães, Matthiesen, Strano Moraes and Costa-Silva.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gene expression analysis of pancreatic cancer EV-treated bone marrow cells. (A) Volcano plot of RNA-Seq of PBS versus EV-treated CD11b⁺ BM cells showing 13 and 28 genes significantly up- and downregulated (red dots and blue dots, respectively), with FDR P-value ≤ 0.05 and fold change > 2 or < −2. (B) Graph plot of the most significant processes of Gene Ontology (GO) enrichment analysis in the “Biological Process” section of up- and downregulated genes, using the Gene Ontology PANTHER Database.