Skip to main content
. 2020 Nov 27;11:551189. doi: 10.3389/fmicb.2020.551189

TABLE 2.

Anti-bacterial activity of synthetic compounds against MRSA, P. aeruginosa, E. coli, and M. tuberculosis.

Synthetic compound MIC (μM)†,‡
MRSA M. tuberculosis E. coli P. aeruginosa
1a 12.5 ± 1.0 1.5 ± 3.0 12.5 ± 5.0 6.2 ± 9.0
1b 100 ± 5.4 25 ± 1.0 100 ± 1.0 100 ± 6.5
2a 12.5 ± 0.7 1.5 ± 1.0 50 ± 1.0 50 ± 1.0
3 12.5 ± 1.0 3.1 ± 0.7 6.2 ± 1.0 3.1 ± 5.0
13 12.5 ± 2.7 0.02 ± 1.1 25 ± 2.0 25 ± 4.0
18 12.5 ± 2.0 12.5 ± 1.0 1.5 ± 4.0 12.5 ± 0.8

Samples were diluted from 100 to 0.0002 μM and incubated with bacteria (starting concentration OD600 = 0.001) under optimum assay conditions as described in the Experimental section. Values represent averages from three independent repeats.