TABLE 3.
Toxicity of synthetic compounds to cell lines.
| Synthetic samples | Minimum toxicity concentration of drug (MTC μM)†,‡,§ |
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| A549 | THP1 | HepG2 | HEK 293 | |
| 1a | >100 ± 4.1 | 50 ± 2.0 | >100 ± 3.0 | 50 ± 0.9 |
| 1b | >100 ± 3.8 | >100 ± 2.0 | >100 ± 0.9 | >100 ± 6.0 |
| 2a | >100 ± 1.0 | 6.5 ± 0.8 | >100 ± 0.8 | 50 ± 4.0 |
| 3 | >100 ± 2.0 | 50 ± 5.0 | >100 ± 1.0 | 25 ± 2.0 |
| 13 | 50 ± 1.4 | 3.1 ± 0.7 | >100 ± 5.2 | 6.5 ± 3.0 |
| 18 | >100 ± 6.0 | >100 ± 9.0 | >100 ± 5.0 | 3.1 ± 8.2 |
†Cells seeded at a concentration of 2 × 105 cells/well; samples diluted 100 to 0.0002 μM. ‡Cells incubated with sample under humidified incubation of 37°C with 5% CO2. §Values represent averages of three independent repeats.