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. Author manuscript; available in PMC: 2020 Dec 11.
Published in final edited form as: Acta Biomater. 2020 Mar 17;108:347–357. doi: 10.1016/j.actbio.2020.03.017

Fig. 3.

Fig. 3.

The expression of pro-IL-1 β and NLRP3. Priming effects of LPS and particles alone on macrophages (n = 4) were analyzed by qRT-PCR and Western blotting. The relative mRNA expression of (a) pro-IL-1 β and (b) NLRP3, and the production of intracellular (c) pro-IL-1 β and (d) NLRP3 proteins were determined after an eight-hour stimulation with Ti, Cr, and Mo particles. Representative Western blot images are included with * illustrating statistically significant difference between indicated conditions (p < 0.05).