Table 1.

Literature Review on Cystic Fibrosis and MRSA management.

Author	No. Pts.	Age (Yrs)	Treatment protocol	Eradication success (%)
Vanderhelst et al. 2013 [12]	11	Range 1-43	Six-month course: 1.o. Rifa 15 mg/kg/day 2.o. Fusidic acid 30 mg/kg/day 3.t. decolonization including muoirocin-containng n. oitment applied to all pts. 3× daily for 5 days Two pts. had to switch to a combination of Rifa.and Clin (one after two weeks, and one after four weeks)	90% Within 6-month period The 10% failure was due to lack of adherence of the treatment
Vanderhelst et al. 2013 [13]	6	Median 21.4	Six-month course: 1.o. Rifa 15 mg/kg/day 2.o. FA 30 mg/kg/day 3.t. decolonization including muoirocin-containng n. oitment applied to all pts 3× daily for 5 days	83%
Fung, L 2012 [14]	3	3,17, and 15	continuous infusion of Vanco (50/40/31) mg/kg/day respectively every 8 h	Eradication is unknown No Nephrotoxicity
Burdge 1995 [15]	2	28 and 31	Two-month course: 1.o. rifa 600 mg daily 2.clin 600 mg bid	100% At 8-month follow up
Kiefer A. 2018 [16]	7	Range 4-30	7-day course: 1.o. Rifa (7.5–10 mg/kg, max. 300 mg twice daily) 2.o. FA (15 mg/kg max. 500 mg three times daily) 3.inhalation therapy with Vanco (4 mg/kg, max. 250 mg, dissolved in 4 ml NaCl 0,9% twice daily)	86%
Banjar 2019	22	Mean 10 ± 7.2	2-weeks course divided: 1.n. Bac in 13 pts. 2.n. Bac + Linezolid in 1 pt. 3.n. Bac + Vanco + Rifa in 3 pts. 4.Vanco + Rifa in 5 pts.	36%

MRSA: Methicillin Resistant Staphylococcus Aureus. Pts. = Patients, Yrs = Years, NaCl = Sodium Chloride. Vanco = Vancomycin, Rifa = Rfampin, Bac = Bactroban, Clin = Clindamycin. n. = Nasal, o. = Oral, t. = Topical, IV = Intravenous. bid = twice-daily, max. = maximum, FA = Fusidic Acid, No. = number of.