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. 2020 Oct 26;11:585130. doi: 10.3389/fendo.2020.585130

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Copyright © 2020 Yumiceba, López-Cortés, Pérez-Villa, Yumiseba, Guerrero, García-Cárdenas, Armendáriz-Castillo, Guevara-Ramírez, Leone, Zambrano and Paz-y-Miño

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UCSC Genome Brower (Human Feb 2009 (GRCh37/hg19 assembly) displaying rs8111699 (highlighted) and tracks representing histone marks and transcription factors in the first intron of STK11. For histone marks peak height is proportional to the signal amplitude with colors representing databases in seven different cell lines*. For transcription factor binding tracks, the length of the box indicates region of occupancy and the darkness is proportional to the signal strength observed in several cell lines. To the right there is the number of cell types contributing to the cluster or a fraction that corresponds the number of cell where the factor was detected out of all cell assayed. The letters represent the cell abbreviation L, HepG2; K, K562; a, adrenal gland; G, GM12878; t, tibial nerve. * 7 Cell lines for histone marks from ECODE: GM12878 (B-lymphocyte, lymphoblastoid), H1-hESC (embryonic stem cells), HSMM (skeletal muscle myoblasts), HUVEC (umbilical vein endothelial cells), K562 (erythroleukemic), NHEK (epidermal keratinocytes), NHLF (lung fibroblasts).