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. 2020 Nov;8(22):1502. doi: 10.21037/atm-20-7145

Figure 3.

Figure 3

The mitochondrial function was impaired by hypoxia and partially recovered by the administration of 100 nM rapamycin. (A) Mitochondrial membrane potential decreased in hypoxia-treated D407 cells. (B) The intracellular ATP concentration decreased in hypoxia-treated D407 cells. (C) Reactive oxygen species (ROS) level increased in hypoxia-treated D407 cells. Asterisks indicate significant difference (**, P<0.01; ***, P<0.001).