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. 2020 Nov;8(22):1521. doi: 10.21037/atm-20-7144

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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OTSCC DEGs in TCGA dataset. (A) Heat map hierarchical-clustering shows 581 DEGs in tumor specimens (TCGA-CV-01) compared with non-tumor samples (TCGA-CV-11). Data are provided in a matrix format, in which rows represent individual genes and columns represent each patient. Each cell in the matrix represents the expression level of a gene featured in an individual patient. (B) Volcano plot illustrating DEGs. Vertical lines denote FC values. The right vertical line corresponds to changes of log2FC >1, while the left vertical line corresponds to changes of log2FC <−1. The horizontal line marks a −log10 P value of 0.05. DEGs, differentially expressed genes; OTSCC, oral tongue squamous cell carcinoma.