Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov;8(22):1522. doi: 10.21037/atm-20-7053

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

PMC Copyright notice

The overexpression or knockdown of maspin can affect the sensitivity of lung cancer cells to docetaxel. Fluorescence qPCR (A) and western blot (B) were used to detect the overexpression of maspin in the lung adenocarcinoma-resistant cell line, SPC-A1/docetaxel (DTX). Fluorescence qPCR (C) and western blot (D) were used to detect the interference efficiency of the lung adenocarcinoma sensitive cell line, SPC-A1, after maspin interference. (E) The MTT assay was used to detect the influence of lung adenocarcinoma drug-resistant cell lines and parent cell lines with maspin overexpression or knockdown on IC50 values of DTX, DDP, and Gem. **, P<0.01.