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. 2020 Nov;8(22):1483. doi: 10.21037/atm-20-5830

Table 1. Comparison of CIBERSORT immune cell fractions between tumor and non-tumor tissues from HCC patients.

Immune cell type CIBERSORT fraction in % of all infiltrating immune cells (mean ± SD)
Tumors (n=14) Non-tumors (n=14) P value
T cells CD8 0.140±0.071 0.192±0.073 0.075
T cells CD4 naive 0.0±0.0 0.0±0.0 1.0
T cells CD4 memory resting 0.071±0.082 0.088±0.066 0.553
T cells CD4 memory activated 0.002±0.008 0.0±0.001 0.408
T cells follicular helper 0.074±0.030 0.066±0.030 0.545
T cells regulatory (Tregs) 0.066±0.040 0.011±0.017 <0.001
T cells gamma delta 0.004±0.009 0.012±0.017 0.109
B cells naive 0.013±0.017 0.020±0.027 0.454
B cells memory 0.022±0.026 0.008±0.016 0.133
Plasma cells 0.065±0.025 0.061±0.022 0.658
NK cells resting 0.008±0.016 0.006±0.009 0.709
NK cells activated 0.040±0.021 0.017±0.019 0.007
Macrophages M0 0.043±0.041 0.0±0.003 0.001
Macrophages M1 0.090±0.030 0.090±0.033 0.965
Macrophages M2 0.143±0.081 0.169±0.054 0.351
Monocytes 0.033±0.024 0.056±0.034 0.056
Dendritic cells resting 0.074±0.059 0.043±0.024 0.085
Dendritic cells activated 0.003±0.007 0.0±0.0 0.160
Mast cells resting 0.003±0.011 0.001±0.003 0.505
Mast cells activated 0.081±0.055 0.125±0.144 0.318
Eosinophils 0.0±0.0 0.0±0.0 1.0
Neutrophils 0.026±0.020 0.033±0.015 0.313

Italic P values indicate significance between individual groups. HCC, hepatocellular carcinoma.