Table 1. Comparison of CIBERSORT immune cell fractions between tumor and non-tumor tissues from HCC patients.
Immune cell type | CIBERSORT fraction in % of all infiltrating immune cells (mean ± SD) | ||
---|---|---|---|
Tumors (n=14) | Non-tumors (n=14) | P value | |
T cells CD8 | 0.140±0.071 | 0.192±0.073 | 0.075 |
T cells CD4 naive | 0.0±0.0 | 0.0±0.0 | 1.0 |
T cells CD4 memory resting | 0.071±0.082 | 0.088±0.066 | 0.553 |
T cells CD4 memory activated | 0.002±0.008 | 0.0±0.001 | 0.408 |
T cells follicular helper | 0.074±0.030 | 0.066±0.030 | 0.545 |
T cells regulatory (Tregs) | 0.066±0.040 | 0.011±0.017 | <0.001 |
T cells gamma delta | 0.004±0.009 | 0.012±0.017 | 0.109 |
B cells naive | 0.013±0.017 | 0.020±0.027 | 0.454 |
B cells memory | 0.022±0.026 | 0.008±0.016 | 0.133 |
Plasma cells | 0.065±0.025 | 0.061±0.022 | 0.658 |
NK cells resting | 0.008±0.016 | 0.006±0.009 | 0.709 |
NK cells activated | 0.040±0.021 | 0.017±0.019 | 0.007 |
Macrophages M0 | 0.043±0.041 | 0.0±0.003 | 0.001 |
Macrophages M1 | 0.090±0.030 | 0.090±0.033 | 0.965 |
Macrophages M2 | 0.143±0.081 | 0.169±0.054 | 0.351 |
Monocytes | 0.033±0.024 | 0.056±0.034 | 0.056 |
Dendritic cells resting | 0.074±0.059 | 0.043±0.024 | 0.085 |
Dendritic cells activated | 0.003±0.007 | 0.0±0.0 | 0.160 |
Mast cells resting | 0.003±0.011 | 0.001±0.003 | 0.505 |
Mast cells activated | 0.081±0.055 | 0.125±0.144 | 0.318 |
Eosinophils | 0.0±0.0 | 0.0±0.0 | 1.0 |
Neutrophils | 0.026±0.020 | 0.033±0.015 | 0.313 |
Italic P values indicate significance between individual groups. HCC, hepatocellular carcinoma.