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. 2020 Nov;8(22):1483. doi: 10.21037/atm-20-5830

Table 2. Comparison of CIBERSORT-selected immune cell fractions between tumor and non-tumor tissues from HCC patients.

Immune cell type CIBERSORT fraction in % of all infiltrating immune cells (mean ± SD)
Tumors (n=8) Non-tumors (n=7) P value
T cells CD8 0.164±0.066 0.198±0.080 0.422
T cells CD4 naive 0.0±0.0 0.0±0.0 1.0
T cells CD4 memory resting 0.043±0.065 0.058±0.047 0.64
T cells CD4 memory activated 0.005±0.011 0.001±0.002 0.372
T cells follicular helper 0.069±0.033 0.077±0.031 0.675
T cells regulatory (Tregs) 0.052±0.035 0.008±0.009 0.007
T cells gamma delta 0.007±0.011 0.020±0.019 0.152
B cells naive 0.018±0.018 0.023±0.030 0.479
B cells memory 0.017±0.028 0.0±0.001 0.132
Plasma cells 0.069±0.031 0.064±0.028 0.759
NK cells resting 0.005±0.012 0.002±0.004 0.578
NK cells activated 0.042±0.027 0.015±0.019 0.05
Macrophages M0 0.047±0.049 0.0±0.0 0.025
Macrophages M1 0.104±0.029 0.094±0.039 0.605
Macrophages M2 0.126±0.053 0.155±0.050 0.326
Monocytes 0.031±0.028 0.055±0.033 0.184
Dendritic cells resting 0.082±0.065 0.035±0.019 0.09
Dendritic cells activated 0.003±0.006 0.0±0.001 0.31
Mast cells resting 0.0±0.0 0.002±0.004 0.369
Mast cells activated 0.093±0.059 0.154±0.183 0.444
Eosinophils 0.0±0.0 0.0±0.0 1.0
Neutrophils 0.021±0.010 0.032±0.012 0.097

Italic P values indicate significance between individual groups. HCC, hepatocellular carcinoma.