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. 2020 Nov;8(22):1501. doi: 10.21037/atm-20-6601

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Fucoidan therapy decreases cell apoptosis in hyperoxia-exposed lung tissues and cultured primary lung fibroblast. (A) TUNEL staining was applied to assess cell apoptosis in lung tissues (×200); (B) the apoptosis of cultured primary lung fibroblasts was evaluated using Hoechst staining (×200). The arrow points to apoptotic cells; (C) the expression of Bcl-2/Bax was measured using western-blot. The experiments were repeated at least three times, and error bars represent ± SD *, P<0.05 versus control group; ^#, P<0.05 versus the hyperoxia group. TUNEL, TdT-mediated DUTP nick end labeling.