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Aspirin inhibited the increase of the proportion of type II muscle fibers in denervated skeletal muscle. (A) Immunofluorescence staining and quantification of fast myosin skeletal heavy chain in TA muscle; (B) Western blot and quantification of sirtuin 1 (SIRT1) and proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α). **, P<0.01 and ****, P<0.0001 versus Ctrl group; #, P<0.05, ##, P<0.01 and ###, P<0.001 versus Den group.
