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. 2020 Nov 27;25(23):5591. doi: 10.3390/molecules25235591

Figure 5.

Figure 5

Cellular and molecular bases of AGE-mediated diabetic nephropathy. NRP-1: neuropilin-1; Nrf2: nuclear factor erythroid 2-related factor 2; ARE: anti-oxidant responsive element (for induction of anti-oxidant enzymes and glyoxalase 1 expression); MGO: methyglyoxal; GO: glyoxal.