| KD025 QD (n = 66) | KD025 BID (n = 66) | Overall (n = 132) | |
|---|---|---|---|
| Median age [yrs (range)] | 53 (21-77) | 57 (21-77) | 56 (21-77) |
| Male | 64% | 50% | 57% |
| Median prior LOT | 3 | 4 | 4 |
| Median time from cGVHD Dx (mos) | 25 | 30 | 28 |
| Severe cGVHD [n (%)] | 45 (68%) | 42 (64%) | 87 (66%) |
| Prior Ibrutinib [n (%)] | 23 (35%) | 22 (33%) | 45 (34%) |
| ≥4 Organs Involved [n (%)] | 34 (52%) | 35 (53%) | 69 (52%) |
| Median prednisone dose (mg/kg/day) | 0.2 | 0.2 | 0.2 |
| Refractory to prior line | 81% (42/52) | 65% (32/49) | 73% (74/101) |
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