Year of transplant	Age at transplant	Donor	Conditioning	GVHD prophylaxis	Engraftment	Outcome	Latest chimerism
1 2011	12y M	8/10 MMUD PBSC (allelic A and C mismatches)	Fludarabine 180mg/m2, alemtuzumab 1mg/kg, treosulfan 14g/m2, thiotepa 10mg/kg	CSA + MMF	Neutrophil D+10, Platelet NA	Died D+46 (Multisystem organ failure from D+7. CVVH, intubation, inotropes. Encephalopathic. Sudden deterioration D+45 ?sepsis)	100%
2 2012	2y M	10/10 MUD PBSC	Fludarabine 150mg/m2, Treosulfan 42g/m2, Alemtuzumab 1mg/kg	CSA + MMF	Neutrophil D+15, Platelet D+13	Alive and well	100% 5years 7m post
3 2019	5y F	10/10 MUD PBSC	Fludarabine 150mg/m2, Treosulfan 42g/m2, Alemtuzumab 1mg/kg	CSA + MMF	Neutrophil D+12, Platelet D+14	Alive and well	CD15 100%, CD19 94%, T cell 89% D+124
4 2019	2y F	Maternal TCRα β/CD19 depleted haploidentical PBSC	Fludarabine 160mg/m2, Treosulfan 42g/m2, Thiotepa 10mg/kg, ATG (grafalon) 15mg/m2), Rituximab 200mg/m2	Nil	Neutrophil D+10, Platelets D+16	Alive and well	100% D+62

[Patient and transplant characteristics]