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TAN inhibited PMA induced NF-κB-p65 and HIF-1α nuclear translocation on HaCaT cells. (A) Immunofluorescence staining of HIF-1α after treatment with tangeretin (50 μM, 24 h) and PMA (100 nM, 4 h), (B) Immunofluorescence staining of NF-κB-p65 after treatment with tangeretin (50 μM, 24 h) and PMA (100 nM, 4 h). Scale bar (100 μM). Magnification = 200×. *** p < 0.001.
