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. 2020 Dec 7;21(23):9325. doi: 10.3390/ijms21239325

Table 1.

List of oncogene products and tumor suppressors that control the autophagy pathway.

Oncogene Product or Tumor Suppressor Effect on Autophagy
Pathway
Reference
(1) mTOR Negative regulator [74,75,76,77,78,79,80]
(2) PTEN Inducer [46,81]
(3) Beclin-1 Inducer [74]
(4) DAPK Inducer [82]
(5) BCL-2; BCL-XL Negative regulator [74]
(6) c-FLIP Negative regulator [83,84]
(7) P53 Negative regulator/Inducer [85,86,87,88]