Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
|
Beclin-1 dependent regulation
|
[99] |
The double-edged sword of autophagy modulation in cancer. |
Stress tolerance increase
|
[74] |
The Roles of Autophagy in Cancer. |
Inflammation downregulation
|
[100] |
Targeting GRP75 improves HSP90 inhibitor efficacy by enhancing P53-mediated apoptosis in hepatocellular carcinoma |
Ras activation
|
[88] |
Autophagy suppresses tumor progression by limiting chromosomal instability |
Ras activation
|
[108] |
Autophagy opposes P53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2-associated hereditary breast cancer
|
P53 suppression
|
[112] |