Table 1.
Characteristics of the patient cohort selected from Razavi et al.23.
| Characteristics | All patients (n = 186) |
Estrogen receptor positive (n = 138) |
|---|---|---|
| Age at diagnosis*—yr | 48 (40–55) | 47 (39–54) |
| PI3K pathway status—no. | ||
| Wild type | 104 (55.9%) | 76 (55.1%) |
| PIK3CA mutation | 68 (36.6%) | 51 (37.0%) |
| PIK3R1 mutation | 6 (3.2%)** | 3 (2.2%) |
| AKT1 mutation | 1 (0.5%)*** | 1 (0.7%)*** |
| PTEN homozygous deletion or mutation | 9 (4.8%) | 8 (5.8%) |
*Shown as median (first and third quartiles).
**One patient has both PIK3CA and PIK3R1 mutations.
***One patient has both PIK3CA and AKT1 mutations.