AAR |
Amino acid restriction |
AARE |
Amino acid response element |
AD |
Alzheimer’s disease |
ADAM10 |
Disintegrin and metalloproteinase domain-containing protein 10 |
AP-1 |
Activator protein 1 |
APP |
Amyloid precursor protein |
AKT |
Protein Kinase B |
AMP |
Adenosine monophosphate |
AMPK |
Adenosine monophosphate kinase |
APP |
Amyloid precursor protein |
ARE |
Antioxidant response elements |
Arf-1 GTPase |
ADP ribosylation factor |
α-SMA |
Alpha smooth muscle actin |
ATF |
Activating transcription factor |
ATG |
Autophagy-related genes |
ATP |
Adenosine triphosphate |
AZF1P |
Nuclear-localized zinc-finger |
BACE |
Beta-secretase 1 |
BAT |
Brown adipose tissue |
BCAA |
Branched-chain amino acids |
BCL-2 |
B-cell lymphoma 2 |
BCL-XL |
B-cell lymphoma-extra-large |
BDNF |
Brain-derived neurotrophic factor |
CA-9 |
Carbonic anhydrase 9 |
CamKKB |
Calcium/calmodulin-dependent protein kinase kinase B |
CASTOR |
Cytosolic arginine sensor for mTORC1 |
CAT |
Catalase |
CCL3 |
Chemokine (C-C motif) ligand 3 |
Cpsf6 |
Cleavage and polyadenylation specific factor 6 |
CK19 |
Cytokeratin-19 |
CR |
Caloric restriction |
CRMs |
Caloric restriction mimetic |
CVD |
Cardiovascular disease |
CYP1 |
Cytochrome P450 |
DMTF |
Drosophila metal-responsive transcription factor |
eIF2 |
Eukaryotic initiation factor 2 |
ER |
Endoplasmic reticulum |
FGF21 |
Fibroblast growth factor 21 |
FOXO3a |
Forkhead box O3a |
GADD34 |
Growth arrest and DNA damage-inducible protein 34 |
GATOR |
GTPase-activating protein toward rags |
GCN2 |
General control nonderepressible 2 |
GDP |
Guanosine diphosphate |
GHS |
Glycinyl-histidinyl-serine |
GLUT1 |
Glucose transporter 1 |
GREB1 |
Growth-regulating estrogen receptor binding 1 |
GSK-3β |
Glycogen synthase kinase-3β |
GTP |
Guanosine triphosphate |
HGPS |
Hutchinson–Gilford progeria syndrome |
HIF1α |
Hypoxia-inducible factor-1α |
HSF1P |
Heat shock factor |
IGF-1 |
Insulin-like growth factor-1 |
IL |
Interleukin |
IRS-1 |
Insulin receptor substrate 1 |
ISR |
Integrated stress response |
JNK |
C-jun N-terminal kinase |
LKB1 |
Liver kinase B1 |
LMX1b |
LIM homeobox transcription factor 1-β |
LPIs |
Longevity-promoting interventions |
MAPK |
Mitogen activator protein kinase |
MEF3 |
Mitochondrial editing factor 3 |
MMP9 |
Matrix metallopeptidase 9 |
Mt |
Metallothionein |
mTOR |
Mammalian target of rapamycin |
mTORC1 |
Mammalian target of rapamycin complex 1 |
mTORC2 |
Mammalian target of rapamycin complex 2 |
NAD+
|
Nicotinamide adenine dinucleotide |
NAM |
Nicotinamide |
ND |
Neurodegenerative diseases |
NF-κB |
Nuclear factor-κB |
Nfκbia |
NFκB inhibitor α |
NRF2 |
Nuclear receptor factor 2 |
Pax6 |
Paired box 6 |
PDK1 |
3-phosphoinositide-dependent protein kinase 1 |
PGC-1α |
Peroxisome proliferator-activated receptor gamma coactivator-1α |
PI3K |
Phosphoinositide 3-kinase |
Pitx2 |
pituitary homeobox 2 |
PRDM14 |
PR domain zinc finger protein 14 |
RagA/B |
Ras-related GTP-binding protein A and B |
RagC/D |
ras-related GTP-binding protein C and D |
Rheb |
RAS homolog enriched in brain |
ROS |
Reactive oxygen species |
S6K1 |
Ribosomal protein S6 kinase |
SAAR |
Sulfur amino acid restriction |
SAM |
S-adenosyl-methionine |
SAMTOR |
SAM sensor upstream of mTORC1 |
Sfpq |
Splicing factor proline and glutamine rich |
Sfrs |
Serine- and arginine-rich splicing factor |
SIRT1 |
Sirtuin 1 |
SOD |
Superoxide dismutase |
SPD |
Starvation pseudodiabetes |
STAT3 |
Signal transducer and activator of transcription 3 |
STAT5A/B |
Signal transducer and activator of transcription 5A/B |
T2D |
Type 2 diabetes |
Timp3 |
Metalloproteinase inhibitor 3 |
TNFα |
Tumor necrosis factor-α |
TSC |
Tuberous sclerosis complex |
Txnip |
Thioredoxin interacting protein |
ULK1 |
Unc-51 Like Autophagy Activating Kinase 1 |
VEGFR |
Vascular endothelial growth factor receptor |
WAT |
White adipose tissue |
WNT |
Wingless-related integration site |
XBP-1 |
X-box-binding protein 1 |
YBX1 |
Y-Box 1 |
Zbt16 |
Zinc finger and BTB domain-containing protein 16 |
Zscan1 |
Zinc finger and SCAN domain-containing 1 |